Diarrhoea: replacing fluids and not missing infection
Diarrhoea can be caused by chemotherapy, antibiotics, infections and reactions after transplant. During neutropenia it can also be a sign of infection. This section explains how to replace fluids, what to eat and when to call at once.

01Short answer
02Simple explanation
Extra fluid each time.
Soft, low-fibre food.
Medicines only with the doctor.
Fever or blood? At once.
03Scientific explanation
Clostridioides difficile: diarrhoea after antibiotics can be an infection with this bacterium; a stool test is needed, and anti-diarrhoea drugs can do harm.
ESPEN: enough energy and protein matter for preventing weight and muscle loss in people with cancer, and nutritional status should be assessed regularly.
NCI: practical eating tips exist for treatment side effects such as nausea, taste changes and mouth sores.
04What happens in the body?
Hygiene
Wash hands with soap after every toilet visit; the family follows the same rule.

Skin care
Gentle cleansing and a barrier cream; tell your team about soreness or pain around the anus.

Dietitian
If you are losing weight, have no appetite or need a special diet, ask to see the hospital dietitian.
Food safety
Food-safety rules for neutropenia (see “Handwashing: the simplest protection” and “Eggs and dairy: safe choices”) apply at every stage.
05Nutrition: four steps
Assess, swap the risky, cook safely, eat regularly.







06Key points at a glance
| Topic | In brief |
|---|---|
Hygiene | Wash hands with soap after every toilet visit; the family follows the same rule. |
Skin care | Gentle cleansing and a barrier cream; tell your team about soreness or pain around the anus. |
Dietitian | If you are losing weight, have no appetite or need a special diet, ask to see the hospital dietitian. |
Food safety | Food-safety rules for neutropenia (see “Handwashing: the simplest protection” and “Eggs and dairy: safe choices”) apply at every stage. |
07Key terms
- Rehydration
- Replacing fluid and salts.
- C. difficile
- A bacterium that can cause diarrhoea after antibiotics.
- Dietitian
- A nutrition specialist.
- Protein
- A nutrient for repairing muscles and tissues.
- Neutropenia
- Low neutrophils.
08Key points
- Replace lost fluid.
- Do not self-medicate.
- Call with warning signs.
- A diet is not a treatment.
- Talk to a dietitian.
09Frequently asked questions
Should I take probiotics?
During neutropenia live-microbe supplements may be a risk; talk to your doctor.
Is milk OK?
It worsens diarrhoea for some; yogurt may be better tolerated.
Can a special diet cure leukemia?
No. Good nutrition helps you cope with treatment, but it does not cure.
10Questions for your doctor
Take these questions to your appointment. The ones you save are collected on the “My questions” page and stay on this device only.
Should I take probiotics?
Is milk OK?
Can a special diet cure leukemia?
12Sources
- CDC. C. diff Basics
- National Cancer Institute. Eating Hints: Before, During, and After Cancer Treatment
- ESPEN. ESPEN practical guideline: Clinical Nutrition in cancer (2021)
- Leukemia & Lymphoma Society. Food and Nutrition
- World Health Organization. Healthy diet fact sheet
- American Cancer Society. Food Safety During Cancer Treatment
- National Center for Complementary and Integrative Health (NIH). Green Tea
- Memorial Sloan Kettering Cancer Center — About Herbs. Green Tea
- MedlinePlus. Caffeine
- National Cancer Institute. Diet and Cancer Risk
Hygiene
Skin care
Dietitian