Sexual health
Leukaemia and its treatment can affect desire, comfort and intimacy. This topic explains, calmly and openly, why this happens and what helps.

01Short answer
02Simple explanation
Sexual health involves body and feelings.
Causes: hormones, GVHD, tiredness, mood.
In women: dryness, pain; in men: desire and erections.
Many problems can be treated.
Most important: talk openly.
03Scientific explanation
In women: according to the NCI, lower oestrogen after treatment can cause vaginal dryness, pain during sex and lower desire; moisturisers and hormone therapy can help.
In men: the NCI notes that lower testosterone, tiredness and some medicines affect desire and erections; medicines and other treatments are available.
After transplant: the COG and NCI note that chronic GVHD can affect the genital lining; regular gynaecology or urology reviews are recommended.
Feelings: the ACS highlights the effect of body image, anxiety and depression on sexual health; psychological and couples counselling help.
04What happens in the body?
Why does it change?
Treatment affects hormones, energy and the body; feelings and relationships can change too. This is a normal reaction.
The role of hormones
Oestrogen and testosterone affect desire and comfort. Low levels can be checked with a blood test.

In women
Vaginal dryness, pain and lower desire. What helps: moisturisers, lubricants, hormone therapy (with your doctor) and pelvic floor physiotherapy.
In men
Lower desire and difficulty with erections. What helps: checking testosterone levels, medicines for erections (with your doctor) and seeing a urologist.
Relationships and feelings
Talking openly with your partner, finding other forms of closeness, and seeing a psychologist or couples counsellor help.

When to call your doctor
Worrying signs — fever, bleeding, new pain, breathlessness — should be reported to your doctor between visits too. Getting in touch early is always better than waiting.
05Supporting sexual health
Steps.







06Possible changes (simplified)
| Change | Possible cause | What helps |
|---|---|---|
| Lower desire | Hormones, tiredness, mood | Doctor, psychologist |
| Vaginal dryness, pain | Lower oestrogen, GVHD | Moisturisers, gynaecologist |
| Difficulty with erections | Testosterone, medicines | Urologist, treatment |
| Anxiety, body image | The experience of treatment | Psychological support |
* Choose treatment together with your doctor.
07Key terms
- Libido
- Sexual desire.
- Oestrogen
- A female sex hormone.
- Testosterone
- A male sex hormone.
- Erection
- The penis becoming firm.
- Lubricant
- A product that reduces friction during sex.
- Couples counselling
- Psychological support for partners together.
08Key points
- Changes are normal.
- Many problems have solutions.
- Talk openly with your doctor.
- Talk with your partner.
- Get your hormones checked.
- Keep infection risk in mind.
09Frequently asked questions
It feels embarrassing to talk to my doctor about this.
Doctors are used to these questions; it is a normal part of health.
Is sex safe during treatment?
It depends on your blood counts; ask your doctor.
Do I need contraception?
Yes, during treatment and for a while after; discuss it with your doctor.
When will this pass?
It often improves with time and treatment.
Does this information replace medical advice?
No. This is general education; only your treating doctor can assess your situation.
10Questions for your doctor
Take these questions to your appointment. The ones you save are collected on the “My questions” page and stay on this device only.
It feels embarrassing to talk to my doctor about this.
Is sex safe during treatment?
Do I need contraception?
When will this pass?
Does this information replace medical advice?
12Sources
- National Cancer Institute. Sexual Health Issues in Women with Cancer
- National Cancer Institute. Sexual Health Issues in Men with Cancer
- American Cancer Society. Fertility and Sexual Side Effects
- MedlinePlus (U.S. National Library of Medicine). Sexual Problems in Women
- MedlinePlus (U.S. National Library of Medicine). Sexual Problems in Men
- Children's Oncology Group. Long-Term Follow-Up Guidelines for Survivors of Childhood, Adolescent and Young Adult Cancers
- National Cancer Institute (NCI). Follow-Up Medical Care
- National Cancer Institute (NCI). Cancer Survivorship
- Cancer.Net (ASCO). Follow-Up Care After Cancer Treatment
- Leukemia & Lymphoma Society (LLS). Long-Term and Late Effects of Treatment