Emergency warning signs
During treatment, some signs need help without waiting. Knowing them in advance protects life.

01Short answer
02Simple explanation
Fever means call now.
If in doubt, do not wait.
03Scientific explanation
In neutropenic patients, fever is the first and sometimes only sign of infection; early antibiotics are vital.
Sepsis is the body’s overwhelming reaction to infection; recognising it early improves the outcome.
04What happens in the body?
Infection
Fever, chills, weakness, and redness or discharge at the central line.
Bleeding and clots
Bleeding that will not stop, black stools, blood in the urine, a suddenly swollen painful leg, breathlessness.

Nervous system
Sudden severe headache, confusion, speech problems, weakness or a seizure.

05The emergency steps
Four steps.






06Key points at a glance
| Topic | In brief |
|---|---|
Infection | Fever, chills, weakness, and redness or discharge at the central line. |
Bleeding and clots | Bleeding that will not stop, black stools, blood in the urine, a suddenly swollen painful leg, breathlessness. |
Nervous system | Sudden severe headache, confusion, speech problems, weakness or a seizure. |
07Key terms
- Febrile neutropenia
- Fever with low neutrophils.
- Sepsis
- A dangerous whole-body reaction to infection.
- Melaena
- Black, tarry stools.
08Key points
- With a fever, call at once.
- Do not wait with bleeding.
- Confusion is urgent.
- Call before taking fever medicine.
09Frequently asked questions
It is midnight. Should I wait until morning?
No, call the emergency number now.
What if it is a false alarm?
The team understands; it is better to be safe.
10Questions for your doctor
Take these questions to your appointment. The ones you save are collected on the “My questions” page and stay on this device only.
It is midnight. Should I wait until morning?
What if it is a false alarm?
12Sources
- National Cancer Institute (NCI). Infection and Neutropenia during Cancer Treatment
- NHS. Sepsis
- National Cancer Institute (NCI). Bleeding and Bruising (Thrombocytopenia) and Cancer Treatment
- World Health Organization (WHO). Sepsis — fact sheet
- National Cancer Institute (NCI). Managing Your Care
- National Cancer Institute (NCI). Questions to Ask about Cancer Treatment
- National Cancer Institute (NCI). Female Fertility and Cancer Treatment
- National Cancer Institute (NCI). Male Fertility and Cancer Treatment
- National Cancer Institute. NCI Dictionary of Cancer Terms: remission
- National Cancer Institute (NCI). Follow-Up Medical Care
Infection
Bleeding and clots
Nervous system