Nails: short, clean, no cuts
Germs collect under the nails, and small injuries around a nail can turn into infection during neutropenia. Some chemotherapy medicines make nails brittle, dark or ridged.

01Short answer
02Simple explanation
Short, clean.
Do not cut: file.
Cuticles: do not cut.
Salons: ask.
03Scientific explanation
NCI: treatment can cause nail changes; keeping nails short and clean and wearing gloves for housework are recommended.
NCI: chemotherapy can lower neutrophils, platelets and red cells, which raises the risk of infection, bleeding and fatigue.
04What happens in the body?
Paronychia
Inflammation around a nail can spread quickly during neutropenia.
Polish
Ordinary polish and acetone-free remover are usually fine; ask your team.
Neutrophils
The first defence against infection; when they are low, hygiene matters most.
Platelets
Help blood clot; when they are low, protect yourself from injury.
05Daily protection: four steps
Wash, protect, check, report.







06Key points at a glance
| Topic | In brief |
|---|---|
Paronychia | Inflammation around a nail can spread quickly during neutropenia. |
Polish | Ordinary polish and acetone-free remover are usually fine; ask your team. |
Neutrophils | The first defence against infection; when they are low, hygiene matters most. |
Platelets | Help blood clot; when they are low, protect yourself from injury. |
07Key terms
- Cuticle
- The thin skin at the base of the nail.
- Emery board
- A tool for filing nails.
- ANC
- Absolute neutrophil count.
- Thrombocytopenia
- A low platelet count.
08Key points
- Keep short.
- File.
- Tell us.
- Wash your hands.
- 38 °C: call.
09Frequently asked questions
My nails have darkened.
This can be caused by medicines; tell your team.
A nail is lifting.
Cover it and tell your team.
What should I watch every day?
Temperature, bleeding, tiredness and the catheter site; tell your team about any change.
10Questions for your doctor
Take these questions to your appointment. The ones you save are collected on the “My questions” page and stay on this device only.
My nails have darkened.
A nail is lifting.
What should I watch every day?
12Sources
- National Cancer Institute. Skin and Nail Changes during Cancer Treatment
- National Cancer Institute. Infection and Neutropenia during Cancer Treatment
- National Cancer Institute. Bleeding and Bruising (Thrombocytopenia) and Cancer Treatment
- National Cancer Institute. Anemia and Cancer Treatment
- World Health Organization. World Hand Hygiene Day
- MedlinePlus (U.S. National Library of Medicine). Peripherally inserted central catheter — flushing
- ICUsteps. Guide to intensive care: effects on your body
- National Cancer Institute (NCI). Support for Caregivers of Cancer Patients
- American Cancer Society. Caregivers and Family
- Macmillan Cancer Support. Support with cancer and anxiety
Paronychia
Polish
Neutrophils